The offering was developed in collaboration with Douro Labs, and its early access program has also seen participation from major firms such as Jump Trading Group and several large banks.
The move will see Cboe contribute real-time, derived market data to serve the global DeFi community.
As part of the agreement, MEMX will form a new cloud-based digital asset entity to consume its exchange data and then periodically share a subset of that with Pyth.
Market maker Jane Street joins growing list of data contributing members on the Pyth Network including Hudson River Trading which joined earlier this month.